tissue TransGlutaminase IgA1

tissue TransGlutaminase IgA1

Ref. A_tTG_G4A9

Human chimeric monoclonal IgA anti-tissue transglutaminase, clone G4A9

 

Obtained from hybridomas developed by HAMIGA® mice immunization with tissue transglutaminase (Operon).

Tissue transglutaminase (tTG) is a enzyme released from cells during inflammation. tTG is suggested to exert at least two crucial roles in celiac disease: as a deamidating enzyme, that can enhance the immunostimulatory effect of gluten, and as a target autoantigen in the immune response. 

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