tissue TransGlutaminase IgA1
Human chimeric monoclonal IgA anti-tissue transglutaminase, clone G4A9
Obtained from hybridomas developed by HAMIGA® mice immunization with tissue transglutaminase (Operon).
Tissue transglutaminase (tTG) is a enzyme released from cells during inflammation. tTG is suggested to exert at least two crucial roles in celiac disease: as a deamidating enzyme, that can enhance the immunostimulatory effect of gluten, and as a target autoantigen in the immune response.