tissue transglutaminase IgG

Human chimeric monoclonal IgG anti-tissue transglutaminase, clone B6F3

Available under purified form or supernatant.

Obtained from hybridomas developed by GammaPrim^® mice immunization with tissue transglutaminase (Operon).

Tissue transglutaminase (tTG) is a enzyme released from cells during inflammation. tTG is suggested to exert at least two crucial roles in celiac disease: as a deamidating enzyme, that can enhance the immunostimulatory effect of gluten, and as a target autoantigen in the immune response.