Human chimeric monoclonal IgM anti-GM1, clone A12C5
Obtained from hybridomas developed by InEps mice immunization with GM1 (Sigma)
GM1 is a ganglioside (glycolipid).
IgM anti-GM1 antibodies occur with increased frequency in the serum of patients with multifocal motor neuopathy. They are also found in some Guillain-Barré syndrome and rare cases of motoneuron diseases.